Frank must make his way through the casinos, shops and eateries of Fortune City including the Uranus Zone, a new sci-fi themed Amusement Park with its own unique mini-games and 'death trap' rides.
New items littered throughout the environment help Frank fight his way through the crowds of zombies. Players can use one of the numerous maintenance rooms to combine the everyday items into weapons of mass zombie destruction. In addition to those taken from Dead Rising 2, combo weapons from Dead Rising 2: Case West and all-new ones are introduced to help kill zombies in even more humorous ways. Tennis ball launchers and motor oil create flaming turrets, rubber alien masks and gems create a mask that shoots lasers, and Uranus Zone Escape Pods combined with fire extinguishers create Cryopods which when placed on a zombie hover in the air freezing zombies underneath. More than 10 new combo weapons have been added to the already robust list of unique and deadly weapons.